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Scientists suggested how an organic molecule affects bacteria that are resistant to drugs and have found that it can suppress and destroy a pathogen that can cause significant disease or, in some circumstances, death. The findings of the study were published in the journal Antibiotics. Pseudomonas aeruginosa is a type of bacteria, often found in hospital patients, which can lead to infections in the blood, lungs (pneumonia), or other parts of the body after surgery. Hydroquinine, an organic compound found in the bark of some trees, was recently found to have bacterial killing activity against the germ and several other clinically important bacteria, including Staphylococcus aureus, Escherichia coli, and Klebsiella pneumoniae. The team behind the discovery, from the University of Portsmouth and Naresuan and Pibulsongkram Rajabhat Universities in Thailand, have now explored the molecular responses of Pseudomonas aeruginosa strains to hydroquinine. They did this by looking at which genes were switched on and which were switched off in response to the drug.
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